Acupuncture and Osteoarthritis
OBJECTIVE:
A patient receiving Acupuncture treatment for osteoarthritis
DESIGN:
A randomized, controlled trial.
SETTING:
Two outpatient clinics (an integrative medicine facility and a rheumatology facility) located in academic teaching hospitals and 1 clinical trial facility.
PATIENTS:
570 patients with osteoarthritis of the knee (mean age [+/-SD], 65.5 +/- 8.4 years).
INTERVENTION:
23 true acupuncture sessions over 26 weeks. Controls received 6 two-hour sessions over 12 weeks or 23 sham acupuncture sessions over 26 weeks.
MEASUREMENTS:
Acupuncture and osteoarthritis – The primary outcomes were changes in the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain and function scores at 8 and 26 weeks. Secondary outcomes were patient global assessment, 6-minute walk distance, and physical health scores of the 36-Item Short-Form Health Survey (SF-36).
RESULTS:
Participants in the true acupuncture group experienced greater improvement in WOMAC function scores than the sham acupuncture group at 8 weeks (mean difference, -2.9 [95% CI, -5.0 to -0.8]; P = 0.01) but not in WOMAC pain score (mean difference, -0.5 [CI, -1.2 to 0.2]; P = 0.18) or the patient global assessment (mean difference, 0.16 [CI, -0.02 to 0.34]; P > 0.2).
Moreover, WOMAC pain score improved more (mean difference, -0.87 [CI, -1.58 to -0.16]; P = 0.003). Additionally, patient global assessment showed greater improvement (mean difference, 0.26 [CI, 0.07 to 0.45]; P = 0.02).
LIMITATIONS:
At 26 weeks, 43% of the participants in the education group and 25% in each of the true and sham acupuncture groups were not available for analysis.
CONCLUSIONS:
Acupuncture seems to provide improvement in function and pain relief as adjunctive therapy for osteoarthritis of the knee when compared with credible sham acupuncture and education control groups.
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